My group is conducting internationally highly competitive research on the quantification of whole joint loading using multi-body simulation. Its work is known for the development of subject-specific musculoskeletal models containing a high level of anatomical detail, especially in the context of cerebral palsy. More recent research activities relate to the development of multi-scale modelling of bone and cartilage adaptation and advanced medical imaging of cartilage to understand degenerative joint diseases. In this context, I aim to elucidate the role of mechanical loading in cartilage homeostasis and disease using multi-axial bioreactor experiments. I am passionate about this new, highly multi-disciplinary research line combining biomedical sciences (human movement science, musculoskeletal modelling, cartilage biology and imaging) and engineering sciences (multi-scale modelling) to optimize exercise regimes for cartilage health.